SALL4 anticorps (Internal Region)
Aperçu rapide pour SALL4 anticorps (Internal Region) (ABIN374800)
Antigène
Voir toutes SALL4 AnticorpsReactivité
Hôte
Clonalité
Conjugué
Application
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Épitope
- Internal Region
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Séquence
- C-DQSKKGKGKP QN
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Specificité
- This antibody detects SALL4.
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Réactivité croisée (Details)
- Species reactivity (expected):MouseSpecies reactivity (tested):Rat
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Purification
- Ammonium sulphate precipitation followed by antigen affinity chromatography using the immunizing peptide
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Immunogène
- Peptide from the internal region of the protein sequence according to NP_780512.2, NP_958797.2, NP_958798.2. Genename: Sall4
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Indications d'application
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Peptide ELISA: antibody detection limit dilution 1: 32000. Western blot: 0.1-0.3 μg/mL. Approx 70 kDa band observed in Rat Spleen and Testis lysates(calculated MW of 66.0 kDa according to NP_958797.2). Additional bands of unknownidentity was also consistently observed at 28+20 kDa. These bands were successfullyblocked by incubation with the immunising peptide. We would appreciate any feedbackfrom people in the field - have any such results been reported with otherantibodies/lysates? Have any further splice variants/modified forms been reported?
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user. -
Restrictions
- For Research Use only
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Concentration
- 0.5 mg/mL
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Buffer
- Tris saline, 0.02 % sodium azide, pH 7.3 with 0.5 % bovine serum albumin
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Agent conservateur
- Sodium azide
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Précaution d'utilisation
- This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Conseil sur la manipulation
- Avoid repeated freezing and thawing.
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Stock
- 4 °C/-20 °C
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Stockage commentaire
- Store at 2 - 8 °C for up to one month or (in aliquots) at -20 °C.
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- SALL4 (Sal-Like 4 (SALL4))
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Autre désignation
- Sal-Like Protein 4 (SALL4)
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Sujet
- Sall4 is a probable transcription factor. Defects in Sall4 are the cause of Okihiro syndrome, also known as Duane radial ray syndrome (DRRS). It is a disorder characterized by the association of forearm malformations with Duane retraction syndrome. Sall4 is also involved in forelimb and heart development in miceSynonyms: Zinc finger protein SALL4
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ID gène
- 99377
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NCBI Accession
- NP_780512
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UniProt
- Q8BX22
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Pathways
- Stem Cell Maintenance, Tube Formation
Antigène
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